Disclaimer: The information supplied on this site is not a substitute for Specialist health care advice or prognosis. In case you have any questions or fears about your well being, be sure to check with a physician.

This medication may perhaps interfere with certain lab checks (like amylase/lipase degrees), perhaps causing Wrong take a look at outcomes. Be sure lab personnel and your doctors know you employ this drug.

Just take your prescribed dose each individual 4 hours as necessary. Usually do not consider in excess of your prescribed dose. When you miss out on a dose, just take your upcoming dose when essential.

Just after halting a CYP2D6 inhibitor, as the consequences of your inhibitor drop, the codeine plasma focus will lessen though the Lively metabolite morphine plasma focus will enhance, which could enhance or lengthen adverse reactions and could result in potentially deadly respiratory despair (see CLINICAL PHARMACOLOGY).

Whilst critical, everyday living-threatening, or deadly respiratory depression can manifest Anytime throughout the use of acetaminophen and codeine phosphate tablets, the danger is best in the course of the initiation of therapy or pursuing a dosage enhance.

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Observe for respiratory depression, Specially for the duration of initiation and adhering to any website increase in dose; close checking will probably be necessary in people at greater possibility and/or All those obtaining concomitant remedies that boost the danger of respiratory depression

Reserve website concomitant prescribing of acetaminophen and codeine phosphate tablets and benzodiazepines or other CNS depressants to be used in get more info patients for whom substitute treatment choices are inadequate (see PRECAUTIONS, more info Drug Interactions).

Acetaminophen and codeine could improve the neuromuscular blocking motion of skeletal muscle mass relaxants and create an elevated diploma of respiratory depression.

These outcomes seem to extend Using the length of remedy. The clinical importance of such findings will not be acknowledged.

Danger of Medication Faults: Make sure precision when prescribing, dispensing, and administering the oral Option; dosing mistakes because of confusion in between mg and mL, and also other codeine solutions of various concentrations may result in accidental overdose and death.

Healthcare vendors are strongly inspired: to accomplish a REMS-compliant schooling system; counsel individuals and/or their caregivers, with each individual prescription, on Risk-free use, critical pitfalls, storage, and disposal; emphasize to individuals and their caregivers the importance of studying the Medication Manual each time it really is furnished by their pharmacist; and take into consideration other instruments to improve patient, home, and Local community security.

Evaluate clients receiving acetaminophen and codeine phosphate tablets and get more info any CYP3A4 inhibitor or inducer for symptoms and indicators which could mirror opioid toxicity and opioid withdrawal when acetaminophen and codeine phosphate tablets are utilised along with inhibitors and inducers of CYP3A4 (see Safety measures, Drug Interactions).

Get healthcare aid right away For those who have any quite major Uncomfortable side effects, such as: fainting, seizure.